RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
miR-1-3p
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
rattus norvegicus
Detection Methods
RT-PCR;western blotting;dual luciferase reporter assay etc.
Target
ATG13
Pathway
PI3K-AKT SIGNALING PATHWAY
PubMed ID
Title
Circulating Exosomal miR-1-3p from Rats with Myocardial Infarction Plays a Protective Effect on Contrast-Induced Nephropathy via Targeting ATG13 and activating the AKT Signaling Pathway
Year
2021
Function
"The circulating exosomal miR-1-3p after myocardial infarction inhibited the contrast medium-induced apoptosis and autophagy of renal tubular epithelial cells, and improved the renal function of rats by targeting ATG13 and activating the AKT signaling pathway."